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Observed genes
Polygenic score
Influential genes: FADS1, FADS2
The FADS1 gene is connected to the metabolism of several omega-3 fatty acids, including docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and their precursor alpha-linolenic acid (ALA).
The FADS2 gene is closely associated with the metabolism of omega-3 and omega-6 fatty acids as well.
About Omega 3 ALA
Omega 3 ALA is a fatty acid found in plants (e.g. nuts, seeds) or vegetable oils. It plays a key role in many aspects of our health and has been shown to have a positive effect on the prevention of heart disease and stroke. It is important to know that all omega 3 acids (ALA, DHA, EPA) are different and have their own specifics.
What happens if you don't get enough?
Omega 3 ALA deficiency symptoms include fatigue, memory problems, dry skin, mood swings, depression, as well as problems with heart and circulation.
Recommendations
Some people might be genetically predisposed to have a lower conversion rate of ALA into EPA and DHA. This means that they need more ALA than others to get the same benefits.
Recommendations
Some people might be genetically predisposed to have a lower conversion rate of ALA into EPA and DHA. This means that they need more ALA than others to get the same benefits.

