Macromo

Omega 3 ALA

AF
Anna Fiserova
September 6, 2023Updated August 13, 2026Reviewed by Konstantin Weiss
Omega 3 ALA
This article is currently being worked on. A more in-depth version will be released soon.

Observed genes

Polygenic score

Influential genes: FADS1, FADS2

The FADS1 gene is connected to the metabolism of several omega-3 fatty acids, including docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and their precursor alpha-linolenic acid (ALA).

The FADS2 gene is closely associated with the metabolism of omega-3 and omega-6 fatty acids as well.

About Omega 3 ALA

Omega 3 ALA is a fatty acid found in plants (e.g. nuts, seeds) or vegetable oils. It plays a key role in many aspects of our health and has been shown to have a positive effect on the prevention of heart disease and stroke. It is important to know that all omega 3 acids (ALA, DHA, EPA) are different and have their own specifics.

What happens if you don't get enough?

Omega 3 ALA deficiency symptoms include fatigue, memory problems, dry skin, mood swings, depression, as well as problems with heart and circulation.

Recommendations

Some people might be genetically predisposed to have a lower conversion rate of ALA into EPA and DHA. This means that they need more ALA than others to get the same benefits.

Recommendations

Some people might be genetically predisposed to have a lower conversion rate of ALA into EPA and DHA. This means that they need more ALA than others to get the same benefits.

Sources

We are currently working on preparing a better list of references and studies. It will be ready soon!

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