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Chronic Periodontitis

NL
Nuno Lemos
September 6, 2023Updated August 13, 2026Reviewed by Konstantin Weiss
Chronic Periodontitis
This article is currently being worked on. A more in-depth version will be released soon.

Observed genes

Polygenic score

Influential genes: LBP,GRIK1,TGIF1

Genetic variations in the LBP gene have been connected to its altered levels and the susceptibility to periodontal diseases.

Elevated GRIK1 expression have been seen in inflamed periodontal tissues, that indicates a potential involvement in periodontitis.

Expression of TGIF1 has been found to be upregulated in periodontal tissues of individuals with periodontitis when compared to those who are in a healthy state.

About Chronic Periodontitis

Chronic periodontitis is a chronic inflammation of the gums, caused by the accumulation of large amounts of dental plaque. At first, it may appear with few symptoms of irritation, swelling, and redness, and slowly progress into the chronic stage over time.

What are the complications?

A delay in diagnosis may result in severe and irreversible damage directly to the teeth and their supporting structures. Advanced stages can put you at danger of local infections and even systemic complications like sepsis.

Recommendations

  • The best strategy to prevent periodontitis is to follow good oral hygiene. Make regular dentist appointments (every 6 or 12 months, unless indicated otherwise by your dentist) to catch any early signs of the disease.

Recommendations

  • The best strategy to prevent periodontitis is to follow good oral hygiene. Make regular dentist appointments (every 6 or 12 months, unless indicated otherwise by your dentist) to catch any early signs of the disease.

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Sources

We are currently working on preparing a better list of references and studies. It will be ready soon!

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