Macromo

Skin Cancer

AF
Anna Fiserova
September 6, 2023Updated August 13, 2026Reviewed by Konstantin Weiss
Skin Cancer
This article is currently being worked on. A more in-depth version will be released soon.

Observed genes

Polygenic score

Influential genes: MC1R,SLC45A2,TYR

The MCR1 gene is well established in the context of melanoma risk (type of skin cancer). This gene controls the type of melanin pigment that is produced by melanocytes: eumelanin or pheomelanin.

The SLC45A2 gene is involved in pigmentation, and its variants have been associated with skin color and susceptibility to skin cancer.

The TYR gene codes for an enzyme that plays a key role in the production of melanin, the pigment that gives color to the skin, hair, and eyes.

About Skin Cancer

Skin cancer is an abnormal growth of skin cells that often results from repeated and prolonged exposure of the skin to ultraviolet radiation. The spectrum of the disease is very wide, ranging from mostly harmless basaliomas to life-threatening melanoma.

What are the complications?

Although highly treatable when detected early, skin cancer can be aggressive depending on the type, and spread to other organs and tissues.

Recommendations

To prevent skin cancer, it's important to protect yourself from ultraviolet radiation. Wear sunscreen year-round, avoid tanning beds, wear protective clothing when outside in the sun and try to avoid it at all during the middle of the day. Check your skin regularly for any new growths and formations, and see a doctor if concerned.

Recommendations

To prevent skin cancer, it's important to protect yourself from ultraviolet radiation. Wear sunscreen year-round, avoid tanning beds, wear protective clothing when outside in the sun and try to avoid it at all during the middle of the day. Check your skin regularly for any new growths and formations, and see a doctor if concerned.

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Sources

We are currently working on preparing a better list of references and studies. It will be ready soon!

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