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Observed genes
Polygenic score
Influential genes: MC1R,SLC45A2,TYR
The MCR1 gene is well established in the context of melanoma risk (type of skin cancer). This gene controls the type of melanin pigment that is produced by melanocytes: eumelanin or pheomelanin.
The SLC45A2 gene is involved in pigmentation, and its variants have been associated with skin color and susceptibility to skin cancer.
The TYR gene codes for an enzyme that plays a key role in the production of melanin, the pigment that gives color to the skin, hair, and eyes.
About Skin Cancer
Skin cancer is an abnormal growth of skin cells that often results from repeated and prolonged exposure of the skin to ultraviolet radiation. The spectrum of the disease is very wide, ranging from mostly harmless basaliomas to life-threatening melanoma.
What are the complications?
Although highly treatable when detected early, skin cancer can be aggressive depending on the type, and spread to other organs and tissues.
Recommendations
To prevent skin cancer, it's important to protect yourself from ultraviolet radiation. Wear sunscreen year-round, avoid tanning beds, wear protective clothing when outside in the sun and try to avoid it at all during the middle of the day. Check your skin regularly for any new growths and formations, and see a doctor if concerned.
Recommendations
To prevent skin cancer, it's important to protect yourself from ultraviolet radiation. Wear sunscreen year-round, avoid tanning beds, wear protective clothing when outside in the sun and try to avoid it at all during the middle of the day. Check your skin regularly for any new growths and formations, and see a doctor if concerned.


